North American Neuromodulation Society

ION Committees

The following is information about Institute of Neuromodulation (ION) committees.

Lead Interface Committee

The Lead and Device Interface Committee will address the issue of standardizing implanted connector designs for neuromodulation devices, as has been done successfully for implanted cardiac pacemakers and defibrillators. Absent compatible connectors, simulator implantation and revision often are constrained, and thus safety, efficacy and cost-effectiveness can be compromised. Connector standards will facilitate independent growth of expertise in the development of leads, implanted generators, power sources, and user interfaces.

Clinical group

Richard North, MD (co-chair)
Pete Konrad, MD PhD (co-chair)
Konstantin Slavin, MD
Ashwini Sharan, MD
Parag Patil, MD PhD
Chris Schade, MD PhD

Engineers

Ben Pless
Jack Judy, PhD
Joe Pancrazio, PhD

Clinical Trial Design Standards Committee

The Clinical trial committee will uphold the mission of ION by promoting research and innovation to advance the field of Neuromodulation to improve health and quality of life for patients. This committee will stand in the capacity of ensuring quality standards in SCS neuromodulation for research and trial design.  It will ensure proper review of the technology and science to ensure future study designs will be of the highest clinical and cost-benefit merit to advance the field and ensure proper reimbursement by the healthcare system.

Brian Kopell, MD (co-chair)
Steve Falowski, MD 
Lawrence Poree, MD PhD
Nathaniel Katz, PhD
John Markman, MD
Richard North, MD
Rod Taylor, PhD
Sam Eldabe, MB ChB FRCA FFPMRCA
Salim Hayek, MD PhD
Vibhor Krishna, MD SM

Basic Science in Neuromodulation Committee

The Basic Science in Neuromodulation Committee will address the tenets of IoN’s vision. Co-chaired by Dr. Lawrence Poree and Dr. Robert Foreman , this committee has been tasked with providing a roadmap to direct basic science research to enhance our understanding of the mechanisms of the action of spinal cord and peripheral nerve stimulation (PNS) for the treatment of pain. The committee will provide a review of what is known and what is not known about the mechanisms of action for SCS and PNS stimulation for pain—and in addition, outline and prioritize scientific questions that will help both industry and governmental funding agencies ultimately improve neuromodulation outcomes for pain management. This committee has been divided into three groups to address their goals; these include the Anatomy/Molecular Group led by Dr. Julie Pilitsis, the Modeling Group led by Dr. Sri Sarma, and the Invitro/Invivo Physiology Group led by Dr. Jeff Ardell and Dr. Lawrence Schramm.

The points below highlight the charge that needs to be addressed by this committee:

  • Identify the problem
  • What makes a discovery meaningful in Neuromodulation?
  • Waveforms?
  • Methods?
  • Applications that define of how the discovery creates Neuromodulation therapy?
  • Define 2-3 fundamental non-clinical procedures with end-points that need to be defined to publish and release discoveries in Neuromodulation
  • Action Items:
  • Meet and develop a roadmap that includes animal anatomical and physiological studies as well as modeling work.
  • Suggest that a primary goal will be to define “pain” by which Neuromodulation devices provide therapy. Examples include using sensors, identifying behavior changes, using genetic testing etc.

Robert Foreman, PhD (co-chair)
Lawrence Poree, MD PhD (co-chair)
Julie Pilitsis, MD PhD
Yun Guan, MD PhD
Jeff Ardell, PhD
Lawrence Schramm, PhD

 

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